Irina Stepanov Selected Research

N'-nitrosonornicotine (nitrosonornicotine)

10/2021	Simultaneous analysis of urinary total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, N'-nitrosonornicotine, and cotinine by liquid chromatography-tandem mass-spectrometry.
1/2016	Exposure and Metabolic Activation Biomarkers of Carcinogenic Tobacco-Specific Nitrosamines.
8/2015	Self-reported Tobacco use does not correlate with carcinogen exposure in smokers with head and neck cancer.
8/2013	Elevated levels of 1-hydroxypyrene and N'-nitrosonornicotine in smokers with head and neck cancer: A matched control study.
6/2013	Tobacco smoke biomarkers and cancer risk among male smokers in the Shanghai cohort study.
9/2011	Urinary levels of the tobacco-specific carcinogen N'-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers.
8/2007	Endogenous formation of N'-nitrosonornicotine in F344 rats in the presence of some antioxidants and grape seed extract.
5/2002	Analysis of tobacco-specific nitrosamines in Moldovan cigarette tobacco.

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Irina Stepanov Research Topics

Disease

25	Neoplasms (Cancer) 10/2021 - 05/2002
14	Lung Neoplasms (Lung Cancer) 01/2023 - 01/2006
7	Carcinogenesis 11/2019 - 02/2009
6	Squamous Cell Carcinoma of Head and Neck 01/2020 - 08/2013
4	Head and Neck Neoplasms (Head and Neck Cancer) 01/2019 - 08/2013
2	Tobacco Use Disorder (Nicotine Dependence) 01/2021 - 02/2010
2	Esophageal Neoplasms (Esophageal Cancer) 05/2014 - 09/2011
1	Mouth Neoplasms (Oral Cancer) 01/2018
1	Anhedonia 01/2018
1	Squamous Cell Neoplasms (Squamous Cell Cancer) 09/2017
1	Lymphoma (Lymphomas) 01/2017
1	Inflammation (Inflammations) 07/2016
1	Substance Withdrawal Syndrome (Withdrawal Symptoms) 01/2011
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2010

Drug/Important Bio-Agent (IBA)

21	CarcinogensIBA 10/2020 - 08/2007
16	Biomarkers (Surrogate Marker)IBA 01/2023 - 07/2007
11	SmokeIBA 10/2020 - 01/2006
9	DNA AdductsIBA 10/2020 - 01/2013
8	CotinineIBA 01/2023 - 09/2011
8	N'-nitrosonornicotine (nitrosonornicotine)IBA 10/2021 - 05/2002
7	Nicotine FDA Link 01/2023 - 01/2011
7	4- (methylnitrosamino)- 1- (3- pyridyl)- 1- butan- 1- olIBA 10/2021 - 09/2011
7	NitrosaminesIBA 09/2017 - 04/2005
4	DNA (Deoxyribonucleic Acid)IBA 11/2019 - 11/2015
4	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 09/2017 - 01/2014
4	4- (N- methyl- N- nitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA 01/2016 - 05/2002
4	GlucuronidesIBA 08/2015 - 04/2005
3	Phosphates (Orthophosphate)IBA 11/2019 - 11/2015
3	nitrosamine 4- (methylnitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA 01/2018 - 11/2015
2	phenanthrene tetraolIBA 01/2023 - 05/2014
2	AcidsIBA 01/2023 - 07/2008
2	phenethyl isothiocyanate (PEITC)IBA 07/2016 - 01/2016
2	1-hydroxypyreneIBA 08/2015 - 08/2013
2	pyridineIBA 07/2008 - 04/2005
1	Acetylcysteine (Siran)FDA LinkGeneric 01/2023
1	hydroxycotinineIBA 01/2023
1	S-phenyl-N-acetylcysteineIBA 01/2023
1	CadmiumIBA 01/2023
1	CreatinineIBA 01/2023
1	Carbon MonoxideIBA 01/2021
1	16S Ribosomal RNAIBA 01/2020
1	Varenicline (Chantix)FDA Link 01/2019
1	Explosive Agents (Explosives)IBA 01/2018
1	N 30IBA 09/2017
1	GuanineIBA 01/2017
1	PolymersIBA 01/2017
1	Adenine FDA LinkGeneric 01/2017
1	IsothiocyanatesIBA 07/2016
1	Dinoprostone (PGE2)FDA Link 07/2016
1	Lobeline (Smokeless)IBA 06/2012
1	Mitochondrial DNA (mtDNA)IBA 02/2009
1	Hydroxy AcidsIBA 07/2008
1	Indicators and Reagents (Reagents)IBA 07/2008
1	N-acetyltalosaminuronic acid (NAT)IBA 04/2005

Therapy/Procedure

2	Tobacco Use Cessation Devices 01/2019 - 02/2010
1	Chemoprevention 10/2020
1	Drug Therapy (Chemotherapy) 01/2019